Absorption / emission max.:

  • 674 nm / 699 nm(in Ethanol)

Molar absorbance:

  • 180.000 M-1cm-1


  • Soluble in water, methanol, DMF, DMSO
  • Bright solid state emission
  • Suitable for protein labeling, microarray experiments,
    FisH microscopy, gel electrophoresis
  • Negatively charged
  • Improved water solubility
  • DY-676


  • DY-676 Diagram

    DY-676 Diagram

  • DY-676 Structure

    DY-676 Structure


Yamashita K., Yoshioka Y., Higashisaka K., Mimura K., Morishita Y., Nozaki M., Yoshida T., Ogura T., Nabeshi H., Nagano K., Abe Y., Kamada H., Monobe Y., Imazawa T., Aoshima H., Shishido K., Kawai Y., Mayumi T., Tsunoda S., Itoh N., Yoshikawa T., Yanagihara I., Saito S., Tsutsumi Y., Silica and titanium dioxide nanoparticles cause pregnancy complications in mice, Nature Nanotechnology 6(2011)321-328.

Deissler V., Rüger R., Frank W., Fahr A., Kaiser W. A., Hilger I., Fluorescent Liposomes as Contrast Agents for In Vivo Optical Imaging of Edemas in Mice, Small 4(2008)1240-1246.

Lisy M.-R., Hartung A., Lang C., Schüler D., Richter W., Reichenbach J. R., Kaiser W. A., Hilger I., Fluorescent Bacterial Magnetic Nanoparticles as Bimodal Contrast Agents, Investigative Radiology 42(2007)235-241.

Lisy M. R., Goermar A., Thomas C., Pauli J., Resch-Genger U., Kaiser W. A., Hilger I., In Vivo Near-infrared Fluorescence Imaging of Carcinoembryonic Antigen-expressing Tumor Cells in Mice, Radiology: 247(2008)779-787.

Hamann F. M., Brehm R., Pauli J., Grabolle M., Frank W., Kaiser W. A., Fischer D., Resch-Genger U., Hilger I., Controlled modulation of serum protein binding and biodistribution of asymmetric cyanine dyes by variation of the number of sulfonate groups, Mol Imaging. 10(2011)488.

Pauli J., Brehm R., Spieles M., Kaiser W. A., Hilger I., Resch-Genger U., Novel Fluorophores as Building Blocks for Optical Probes for In Vivo Near Infrared Fluorescence (NIRF) Imaging, Journal of Fluorescence 20(2010)681-693.

Hoffmann S., Vystrcilova L., Ulbrich K., Etrych T., Caysa H., Mueller T.,  Mäder K., Dual Fluorescent HPMA Copolymers for Passive Tumor Targeting with pH-Sensitive Drug Release: Synthesis and Characterization of Distribution and Tumor Accumulation in Mice by Noninvasive Multispectral Optical Imaging, Biomacromolecules, 13(2012)652-663.

Lisy M. R., Lehmann F., Kaiser W. A., Hilger I., Czerney P., Schüler E., Diagnosis of peritonitis using near-infrared optical imaging of in vivo labeled monocytes-macrophages, J. Biomed. Opt., 11(2007) 064014.

Lu X., Jin T., Jin Y., Wu L., Hu B., Tian Y., Fan X., Toxicogenomic analysis of the particle dose-and size-response relationship of silica particles-induced toxicity in mice, Nanotechnology 24(2013)015106.

Laabs E., Béhé M., Kossatz S., Frank W., Kaiser W. A., Hilger I., Optical Imaging of CCK2/Gastrin Receptor-Positive Tumors With a Minigastrin Near-Infrared Probe, Investigative Radiology, 46(2011)196-201.

Nabeshi H., Yoshikawa T., Matsuyamaa K., Nakazato Y., Matsuo K., Arimori A., Isobe M., Tochigi S., Kondoh S., Hirai T., Akase T., Yamashita T., Yamashita K., Yoshida T., Nagano K., Abe Y., Yoshioka Y., Kamada H., Imazawa T., Itoh N., Nakagawa S., Mayumi T.,  Tsunoda S., Tsutsumi Y., Systemic distribution, nuclear entry and cytotoxicity of amorphous nanosilica following topical application, Biomaterials, 32(2011)2713-2724.


Kossatz S., Béhé M., Mansi R., Saur D., Czerney P., Kaiser W. A., Hilger I., Multifactorial diagnostic NIR imaging of CCK2R expressing tumors, Biomaterials, 34(2013)5172-5180.


Available Modifications

Available Modifications Molecular Weight (g · mol-1) Molecular formula Productnumber MSDS
Carboxylic acid 808.95 C42H45N2O9S2Na 676-00 Download
NHS-ester 906.02 C48H48N3O11S2Na 676-01 Download
Amino-derivative 829.06 C44H52N4O8S2 676-02 Download
Maleimide 931.08 C48H51N4O10S2Na 676-03 Download


Available Modifications Amount Pr.nr. Price Qty. Order
DY-676, Carboxylic acid 1 mg 676-00 117.60 €
DY-676-NHS-ester 1 mg 676-01 147.00 €
DY-676-NHS-ester, portionized 5 x 0.2mg 676-01A 175.00 €
DY-676, aminomodified 1 mg 676-02 189.00 €
DY-676-Maleimide 1 mg 676-03 189.00 €

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